Diagnosis of vascular prosthesis infection: PET or SPECT?

The well-established gold standard for imaging infection is scintigraphy with radiolabeled autologous white blood cells (WBCs). Indeed, 2 years ago, in a metaanalysis of all papers published in the previous 20 years on imaging techniques for the diagnosis of infection (1–4), the importance of WBC scanning in this field clearly emerged, with few exceptions. In particular, for the diagnosis of vascular graft infection, although scintigraphy with WBCs was found to be most accurate, the authors concluded that the new hybrid modalities SPECT/CTand PET/CTwould have highly enhanced the use of WBCs and